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Find Out How To Use Granzyme B In Research

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Find Out How To Use Granzyme B In Research

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byAlma Abell

Both Granzyme A and B are serine proteases that can mediate apoptotic signaling for CTL and NK cells. Both options are synthesized as an inactive proenzyme, and they’re both stored within the cytolytic granules. They’re also released by the effector cells during degradation. Either antibody is useful for localization of the granzyme B-containing granules and to help characterize activated NK and CTL cells.

More Information

Granzyme B is designed for use as a research tool only and shouldn’t be used to diagnose illness or disease in patients. There is no known clone, and it uses a synthetic peptide from the N-terminus of the human antibody by the same name. It uses a Rabbit IgG isotype with an undetermined epitope. Likewise, its molecular weight is 32 kDa.

Applications

Granzyme B is designed for Immunohistochemistry applications. To prepare the specimen, you should use paraffin-embedded or Formalin-fixed tissue that is suitable for use. Your slides should be deparaffinized appropriately, usually with xylene or one of its alternatives.

When you choose the concentrated version of the formula, it is necessary to dilute the antibody using a ratio of 1:100, though this is an estimation. Because it can only be used in IHC applications, there is a pre-diluted form available for purchase, as well.

To retrieve the antigen, you will want to boil the tissue sections in a 10mM citrate buffer with a pH of 6.0 for 10 minutes. Then, cool it to room temperature for 20. After it has cooled the appropriate length of time, you should incubate for 10 more minutes. Make sure to wash the slides and rinse them with PBS-Tween between steps.

The Granzyme B antibody is perfect for those studying NK and CTL cells. Visit Spring Bioscience now to learn more.

  • 24 Sep, 2021
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2008-09 Wikipedia for Schools goes online

Wednesday, October 22, 2008

This article mentions the Wikimedia Foundation, one of its projects, or people related to it. Wikinews is a project of the Wikimedia Foundation.

Monday saw the latest edition of the vetted version of Wikipedia, which is aimed at educational use, go quietly online. The extensively revised version covers over five thousand topics, targeting the eight to seventeen years age group. Partnerships with the Shuttleworth Foundation and the Hole in the Wall project will see it distributed in South Africa and India as well as copies being available globally via the offices of SOS Children UK’s umbrella organisation, SOS Kinderdorf worldwide.

First launched in 2006 as a 4,000 article edition, the extract of Wikipedia has employed hi-tech distribution methods, as well as offering a website version which has steadily climbed up in ranking to above other reviewed Wikipedia rivals and copies; the 2007 version was available on the BitTorrent peer to peer network to keep distribution costs down and was equivalent to a fifteen-volume printed encyclopedia. Monday’s release is compared to a twenty-volume print edition.

Our goal is to make Wikipedia accessible to as many people as possible around the world, and SOS Children is a great partner that helps us make that happen.

Key to the process for selecting articles is the English National Curriculum and similar educational standards around the world. The initial vision was to bring this wealth of knowledge to schools where access to the Internet was poor or unavailable, but copies of Wikipedia for Schools can be found on many first world school intranets and web servers. Among the compelling reasons to adopt the project are the vetting and additional study materials which overcome the oft-publicised concerns many educators have with the million article plus Wikipedia that anyone can edit.

In today’s press release announcing the launch, Wikimedia Foundation Executive Director Sue Gardner expressed delight at seeing the project bring out a new version, “Our goal is to make Wikipedia accessible to as many people as possible around the world, and SOS Children is a great partner that helps us make that happen. Wikipedia is released under a free content license so that individuals and institutions can easily adapt, reuse and customize its content: we encourage others, like SOS Children, to do exactly that.”

Running 192 schools in the developing world, SOS Children sees Wikipedia for Schools as a key piece in fulfilling the educational aspect of their mission. SOS Children’s Chairwoman, Mary Cockcroft gave us an introduction and, a Wikipedia administrator himself, the charity’s CEO Andrew Cates spoke to Wikinews at length about the project.

You are part of SOS-Kinderdorf International, can you explain a little about how this works in terms of distributing funds raised in the UK and involving UK citizens in work outside the country?

Mary Cockcroft: SOS Children[‘s Villages] is a “club” of member charities in 130 countries helping orphans and vulnerable children. The club elects SOS-Kinderdorf International as secretary. SOS is a large organisation whose members in aggregate turned over $1bn in 2007, and whose projects include owning and running 192 schools and family-based care for 70,000 children. However much of these funds are raised locally, with for example the member charities in each of India, Pakistan and South Africa raise considerably more funds in their own country than SOS UK does from the UK. Nonetheless SOS Children UK principally raises funds to finance projects in the developing world, and has only financially small projects in the UK (such as the Schools Wikipedia, which is very low cost because of extensive use of volunteers). This year we expect about 80% of our UK income will leave the UK for overseas SOS associations, and some of the remaining 20% will pay for project oversight. We do not spend money in the UK on Direct Mail or TV advertising. Our UK office is involved in overseeing projects we finance and a small number of high-skilled volunteers from the UK help overseas. However around 98% of SOS staff worldwide are local nationals, as are most volunteers.

((WN)) How much work does the UK charity actually carry out within the home country? Are there failings within the government system for orphans and other needy children that you feel obliged to remedy?

MC: We are deeply unhappy about the situation of children in out-of-home care in the UK. However our care model of 168 hour-a-week resident mothers does not fit with the UK philosophy for children without parental care. Internationally SOS always has a policy of sharing best practice and we are working to improve understanding of our way of working, which appears to us to have far better outcomes than the existing one in the UK. Ultimately though the legal responsibility for these children lies with government and we cannot remedy anything without their invitation.

((WN)) Who first came up with the idea of doing a vetted Wikipedia extract? What was the impetus? Was it more for the developing world than first world?

Andrew Cates: I honestly cannot remember who first suggested it, but it came from somewhere in the Wikipedia community rather than from the charity. The original product was very much pitched at the developing world where the Internet is only available if at all over an expensive phone line. I worked in West Africa 1993-1996 and I know well at how thirsty for knowledge people are and how ingenious they will be in overcoming technical obstacles if the need for infrastructure is removed.

((WN)) In reading past year’s announcements there’s some pride in the project being picked up and used in the first world, was this expected or a pleasant surprise?

AC: It was a pleasant surprise. I don’t think we had realised what the barriers schools faced in using the main Wikipedia were. It isn’t just pupils posting material about teachers or meeting strangers: the “Random Article” button on every page could potentially deliver an article on hardcore porn. We had already started when discussion broke on banning Wikipedia from classrooms and I am sure we benefited from it.

((WN)) Can you give an outline of the selection and vetting process? Is it primarily Wikipedians working on this, or are people from the educational establishment brought in?

AC: It was a long and painful process, even with a really good database system. Articles were taken into the proposal funnel from three main sources: direct proposals for inclusion from Wikipedians, lists which came from the Release Version team and proposals drawn up from working through National Curriculum subjects by SOS volunteers. In a few cases where we felt articles were missing we asked the community to write them (e.g. Portal:Early Modern Britain, which is a curriculum subject, was kindly written just for us): These “proposals” were then looked at by mainly SOS volunteers (some onwiki, some offline). Our offices are in the middle of Cambridge and we get high quality volunteers, who skim read each article and then compared two versions from the article history by credible WP editors a significant period apart (this picks up most graffiti vandalism which runs at about 3% of articles). Once they had identified a “best” version they marked any sections or text strings for deletion (sections which were just a list of links to other articles not included, empty sections, sex scandals etc). A substantial sample of each volunteers work was then doubled checked for quality by one of two office staff (of whom I was one). We then have a script which does some automated removals and clean ups. Once we had a selection we posted it to relevant wikiprojects and a few “experts” and got any extra steers.

((WN)) Will you be making use of BitTorrent for distribution again this year? Was it a success in 2007?

AC: BitTorrent was a bit disappointing in that it got us the only substantial criticisms we received online. A lot of people find it too much effort to use. However for the period we offered a straight http: download we had huge problems with spiders eating vast bandwidth (the file is 3.5G: a few thousand rogue spider downloads and it starts to hurt). As per last year therefore our main two channels will be free download by BitTorrent and mailing the DVDs free all over the world. At a pinch we will (as before) put straight copies up for individuals who cannot get it any other way, and we have some copies on memory sticks for on distributors.

((WN)) Is it your opinion that the UK Government should be encouraging the adoption of projects like this as mainstream educational resources?

AC: Clearly yes. We have had a very enthusiastic reaction from schools and the teaching community. We think every school should have an intranet copy. We expect the Government to catch on in a few years. That is not to say that Wikipedia is as good as resources developed by teachers for teachers such as lesson plans etc. but it is a fantastic resource.

((WN)) You’re a Wikipedia administrator, all too often a thankless task. What prompted you to get involved in the first place? What are the most notable highs and lows of your involvement with the project?

AC: Funnily the thing I have found most amazing about Wikipedia is not widely discussed, which is the effect of Wikipedia policies on new editors. I have seen countless extreme POV new editors, who come in and try to get their opinions included slowly learn not only that there are other opinions to consider but that elements of their own opinion which are not well founded. Watching someone arrive often (on pages on religions for example) full of condemnation for others, gradually become understanding and diplomatic is one of the biggest buzzes there is. The downside though is where correcting things which are wrong is too painfully slow because you need to find sources. I was a post-doc at Cambridge University in combustion and I know the article on Bunsen burners has several really significant errors concerning the flame structure and flow structure. But sadly I cannot correct it because I am still looking around for a reliable source.

((WN)) Do you believe schools should encourage students to get involved contributing to the editable version of Wikipedia? Does SOS Children encourage those who are multilingual to work on non-English versions?

AC: I think older students have a lot to learn from becoming involved in editing Wikipedia.

((WN)) To close, is there anything you’d like to add to encourage use of Wikipedia for Schools, or to persuade educators to gain a better understanding of Wikipedia?

AC: I would encourage people to feed back to the project online or via the charity. The Wikipedia community set out to help educate the world and are broadly incredibly well motivated to help. As soon as we understand what can be done to improve things people are already on the task.

((WN)) Thank you for your time.

Retrieved from “https://en.wikinews.org/w/index.php?title=2008-09_Wikipedia_for_Schools_goes_online&oldid=2583732”
  • 22 Sep, 2021
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3 Reasons Why You Should Get An Alaskan Husky

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By Clarence Clark

Contrary to popular belief, the Alaskan husky is not an official breed of the popular husky dogs, but rather, are descendents of other dog breeds such as the Siberian husky, Border Collie, German shepherd and Alaskan Malamute. Weighing on an average of 35 to 65 pounds and growing to about 24 inches high, the Alaskan husky makes a popular choice of pets for many dog owners. We offer you 3 reasons why you should get an Alaskan husky.

Firstly, Alaskan huskies are generally gentle, docile and lively dogs, which allow them to suit the needs of a family with children. Warm and friendly, the Alaskan husky interacts well with children, other breeds of dogs as well as random visitors at its owner’s house. This is an advantage for families with young children who may have other dogs as well as a constant stream of visitors from time to time. In comparison, other breeds of large dogs such as the German shepherd can be pretty much defensive and react negatively to strangers as well as other breeds of dogs around the house. Given such a situation, it is little wonder why the Alaskan husky makes such a popular choice for a dog amongst dog owners.

Moreover, the Alaskan husky requires minimum upkeep in terms of grooming. Most people believe that the thick coat of the Alaskan husky would mean grooming sessions on a regular basis each week. In reality, this is not true. In general, Alaskan huskies require a minimal amount of maintenance which means you would rarely be required to brush them. However, they shed their coats pretty badly two times per year. During this period, special care and attention must be given, and you would need to brush them on a regular basis. This compares pretty well as compared to other dogs which require regular grooming sessions in order to maintain the upkeep of their coats of fur.

[youtube]http://www.youtube.com/watch?v=dUnWDUZ3k6w[/youtube]

Lastly, Alaskan huskies are favored as pets as they are relatively easy to train. Training, however, is necessary under all circumstances as the Alaskan husky can get pretty willful and engage in a variety of destructive acts around the home if not trained properly. These acts include digging holes in your garden, tearing fabrics such as curtains and clawing your furniture to bits. Fortunately, as mentioned earlier, training is relatively easy. As working dogs, Alaskan huskies are relatively intelligent. Training can be done either by yourself or with the help of a professional dog trainer. In any case, training should cover a wide variety of skills such as toilet training, basic household discipline as well as social skills. Use the method of reinforcement for training your Alaskan husky in order to achieve maximum effectiveness.

In all, the reasons why you should consider getting an Alaskan husky are not limited to those mentioned above. In any case, it is essential to assess your own commitment level before making that decision to adopt an Alaskan husky. After all, adopting a dog is not only about fun and laughter, but commitment and responsibilities.

About the Author: Clarence Clark is an avid Husky dog lover providing valuable advice at

huskytime.com

for fellow Husky dog lovers. Where he shares

Husky info

and training tips with Husky lovers worldwide.

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  • 22 Sep, 2021
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Device explodes on London Tube train at Parsons Green

Friday, September 15, 2017

This morning local time an explosion, now officially considered a terrorist incident, was reported on a London underground train which was stopped at Parsons Green in south-west London.The explosion has been officially confirmed caused by an improvised device placed in a white bucket inside a Lidl shopping bag. Reports also indicate a timer attached to the explosive. At least 29 people were injured, NHS England said this afternoon.

Officers and ambulance staff were on the scene this morning, with reports of burn and crush injuries. Detectives and MI5 were investigating.

BBC News presenter Sophie Raworth described seeing a woman on a stretcher with face and leg burns.

In a statement after the incident, British Prime Minister Theresa May said, “My thoughts are with those injured at Parsons Green and emergency services who are responding bravely to this terrorist incident.”

Retrieved from “https://en.wikinews.org/w/index.php?title=Device_explodes_on_London_Tube_train_at_Parsons_Green&oldid=4627161”
  • 20 Sep, 2021
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Thirteen dead, several wounded in Fort Hood, Texas shooting

Thursday, November 5, 2009

The United States Army has confirmed that thirteen people have been killed after a shooting rampage at the Fort Hood army base in Texas. An additional thirty are reported wounded, and the gunman is in stable condition after being shot by military police. Two other soldiers are in detention.

The incident took place at a deployment readiness center. According to local congressman John Carter, shooting broke out shortly before a graduation ceremony.

The gunman has been identified as an army officer, Major Malik Nadal Hasan. He is a mental health professional, presumably either a psychologist or psychiatrist, according to an unnamed defense official. Two other suspects were in custody, the base commander, Lieutenant-General Bob Cone, said.”Our investigation is ongoing, but preliminary reports indicate that there was a single shooter,” Cone said at a news conference. “The shooter is not dead, but in custody in stable condition.”

Initial reports said that the gunman had been shot to death by military police; however, General Cone now says that the man is in custody and is in the hospital with injuries, but is in stable condition. FOX40 News in Sacramento managed to record a military spokesperson commenting on why the media wasn’t informed about the status of the gunman until four hours after the initial announcement was made that he had been fatally shot. That military spokesman replied, “the doctors didn’t know who they were working on.”

When asked at the conference whether Hasan’s attack might have been a terrorist act, General Cone replied that “I couldn’t rule that out, but I’m telling you that right now the evidence does not suggest that.”

It is not currently clear if those killed and wounded are civilian or military. The gunman is reported to have been in uniform and using handguns. Eyewitnesses claim at least one man was armed with a high-power sniper rifle. The chief of media at the base, Christopher Hogue, said to reporters that “the only one we know who was shooting was killed and he had two handguns.”

There may have been other people involved in the shooting, however. “We […] have apprehended two additional soldiers that are suspects. There were eyewitness accounts that there may have been more than one shooter,” General Cone said.

Effective immediately Fort Hood is closed. This is not a Drill. It is an Emergency Situation.”

The Killeen Independent School District said that all schools in the area were placed on lockdown. The base was closed down following the incident as well. “Effective immediately Fort Hood is closed,” a statement on the Fort Hood website read. “This is not a Drill. It is an Emergency Situation.” The website appears to have gone down shortly after the announcement.

A serviceman at the base described his experiences to the BBC. “I heard the emergency announcement over the speakers outside and saw people rushing to get indoors. In our office we’re okay but we’re hearing about the deaths. […] We are still on lockdown. I am hearing that at least nine people may be dead.”

Greg Schannep, a retired colonel, was heading to the 2 P.M. graduation ceremony when he heard gunshots and saw an injured soldier run past him. “Initially, I thought it was a training exercise,” he recounted, as quoted by the New York Daily News. “A soldier came running past me and said ‘sir, there is someone shooting.’ As he ran past me I saw blood on his back. I don’t think he even knew he had been shot.”

“It’s chaotic,” said the director of a local coffee shop near the base, as quoted by the Associated Press. “They’re just saying that they’re under attack they don’t know what’s going on. […] The phones are jammed. Everybody is calling family members and friends. Soldiers are running around with M-16s.”

The authorities are still gathering information about the shooting, according to Homeland Security spokeswoman Sara Kuban. “DoD [Department of Defense], DHS [Department of Homeland Security], FBI and other members of the intelligence community are assessing and gathering facts about the shooting. Because this is early in this event, we cannot at this time confirm motives behind these shootings,” she said.

The Scott & White Memorial Hospital in the town of Temple received ten of the injured victims from the attack. Its website has posted an appeal for blood donations. “Due to the recent events on Fort Hood, we are in URGENT need of ALL blood types,” it said. The hospital received 200 blood donations since 2:45 P.M. local time.

The hospital was soon closed to visitors after the wounded people were received. “[We are] no longer open to visitors as we focus our attention upon the victims and their families,” a statement on the website said. The associate system chief medical officer said that they did not have specific information on their conditions. “We get patients like this, but not usually all at once,” said director Glen Couchman.

Another health facility, the Metroplex Adventist Hospital, received seven other victims. The hospital stated that one of them was soon pronounced dead, and two others, including an EMS paramedic, are in surgery.

Fort Hood is situated in the town of Killeen. It is the largest military base in the world, houses around 40,000 US troops, and is about 100 kilometres (60 miles) north of Austin. It has been compared to a small town, with its own schools, convenience stores, and even two museums.

This is not the first time Killen has witnessed a shooting spree. The town was the site of the worst shooting spree in American history until the Virginia Tech massacre, when on October 16, 1991, George Jo Hennard drove his truck through the front window of Luby’s Cafeteria and proceeded to shoot and kill 23 people and wound another 20, before commiting suicide in what is know as the Luby’s massacre. It should be noted Major Hasan is an alumnus of Virginia Tech.

Hasan’s motives for the shooting spree were not immediately clear, however, Texas Senator Kay Bailey Hutchison told the FOX news agency that “I do know that he has been known to have told people that he was upset about going [to Iraq].”

[Going to Iraq] was probably his worst nightmare

A cousin of the gunman, Nader Hasan, told FOX that his cousin had been ordered to deploy to Iraq, but was unwilling to do so. “We’ve known over the last five years that was probably his worst nightmare,” he said.

According to Nader, Nidal is a US-born Muslim who had joined the military after finishing high school, and was a graduate of Virginia Tech, where he received a bachelor’s degree in biochemistry. He was also a member of the ROTC, and used to be a psychiatrist at the Walter Reed Army Medical Center in Washington, D.C.

“He was a psychiatrist at Walter Reed dealing with the people coming back and […] trying to help them with their trauma,” Nader said.

Retired colonel Terry Lee told FOX that “[Hasan] said maybe Muslims should stand up and fight against the aggressor. At first we thought he meant help the armed forces, but apparently that wasn’t the case. Other times he would make comments we shouldn’t be in the war in the first place.”

Security officials said that some Internet postings made half a year ago, discussing suicide bombings and other forms of violence, appeared to have been posted by Hasan, but this has not been officially confirmed.

Some army bases around the US increased security measures following the attacks. “The bottom line for us is that we are increasing security at our gates because the threat hasn’t yet been defined, and we’re reminding our Marines to be vigilant in their areas of responsibility,” said the public affairs officer for the Marine Corps Air Station in Yuma, Arizona, Captain Rob Dolan.

We don’t have reason to believe that this is anything other than an isolated incident

However, a spokesman for the Department of Defense said that the attack appeared to be an isolated incident. “This is an isolated and tragic case and we’re obviously in the process of obtaining more information as the events unfold,” said Lieutenant Colonel Eric Butterbaugh.

“We don’t have reason to believe that this is anything other than an isolated incident,” an army spokesman from Fort Lewis in the state of Washington, Joe Piek, commented. “We don’t normally discuss security operations at the post anyways, but I am sure this is something that our security law enforcement will be reviewing. As we are watching and listening, there is a lot we don’t know.”

…a horrific outburst of violence

President Barack Obama described the incident as “a horrific outburst of violence” in a press conference in Washington D.C., going on to say, “It is difficult enough when we lose these brave men and women abroad, but it is horrifying that they should come under fire at an army base on US soil. […] We will make sure that we get answers to every single question about this horrible incident. We are going to stay on this.”

Texas Senator Hutchison released a statement regarding the incident. “I am shocked and saddened by today’s outburst of violence at Fort Hood that has cost seven of our brave service members their lives and has gravely injured others. My heart goes out to their loved ones,” she said.

“Our dedicated military personnel have sacrificed so much in service to our country, and it sickens me that the men and women of Fort Hood have been subjected to this senseless, random violence. I know all Americans share this concern for the soldiers and their families who are affected by this tragedy,” the statement continued.

Robert Gates, the Defense Secretary, expressed his sympathy to those affected by the attack. “I can pledge that the Department of Defense will do everything in its power to help the Fort Hood community get through these difficult times,” he said in a statement.

Vice President Joe Biden also offered his condolences. “We are all praying for those who were wounded and hoping for their full and speedy recovery. Our thoughts and prayers are also with the entire Fort Hood community as they deal with this senseless tragedy,” he remarked.

“I was saddened to learn of the tragic incident at Fort Hood. Laura and I are keeping the victims and their families in our thoughts and prayers during this difficult time,” wrote former president George W. Bush in a statement from his office in Dallas.

The state’s governor, Rick Perry, ordered all flags in Texas to be flown at half-staff until Sunday. “[I am] keeping those affected by today’s incidents in our thoughts and prayers,” he said.

The junior senator from Texas, John Cornyn, also issued a statement. “My heart goes out to the victims of the tragedy that occurred today at Fort Hood, as well as their families. Fort Hood is one of our nation’s finest and largest military installations, and a place that has long been a source of pride for Texans, and for all Americans who value the selfless service and sacrifice of our men and women in uniform,” the statement read.

“It is imperative that we take the time to gather all the facts, as it would be irresponsible to be the source of rumors or inaccurate information regarding such a horrific event. Once we have ascertained all the facts, working with our military leaders and law enforcement officials on the ground, we can determine what exactly happened at Fort Hood today and how to prevent something like this from ever happening again.”

Retrieved from “https://en.wikinews.org/w/index.php?title=Thirteen_dead,_several_wounded_in_Fort_Hood,_Texas_shooting&oldid=3291956”
  • 19 Sep, 2021
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What Will A Tummy Tuck Do For You?

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Submitted by: Jackson Alex

Pregnant state can lead to important modifications in a woman s body. These changes are usually detectable in the tummy area such as sagging skin area, vulnerable muscles, scars, hormonal alterations, physical stress of carrying a baby and lack of breast fullness. While pregnant, the stomach skin is stretched and also sagged due to the growth of the baby. So many women are usually anxious to regain their pre-pregnancy physique quickly following delivery.

The reason why tummy tuck

Many women aren’t happy with their post-pregnancy body since they are trying to fix their trouble with an exercise program as well as a nutritious diet, however it won’t fix. These issues may be fixed as well as bring back a woman s physique to its pre-pregnancy with tummy tuck. It is more frequently referred as tummy tuck. Abdominoplasty is a plastic surgery process which removes loose skin and excess fat through the lower stomach as well as strengthens your tummy muscle mass to get improved tone, contour and also functionality of the tummy.

[youtube]http://www.youtube.com/watch?v=hEyjKCH_C28[/youtube]

Doctor s advice

Prior to having the abdominoplasty treatment, it is advisable to consult the plastic surgeon that is focused on the abdominoplasty procedure. He’ll analyze directly as well as assess the amount of body fat within your abdomen and the condition of your stomach muscles. During assessment, you ought to discuss your medical history including pregnancies, health issues, medicine allergic attack, earlier surgical treatments and also medicines that are using at present. Based on these factors your plastic surgeon will decide which kind of method is exactly fitted to your condition as well as ask him how the abdominoplasty can help you.

Abdominoplasty after having a baby

The cosmetic surgeon will probably suggest the sufferers to wait for nine months following delivery as during this time period your skin to tighten up by itself as well as the uterus shrink to the regular size. Abdominoplasty could be the surgical procedure for the stomach in order to eliminate the extra transferred weight and also skin that will accumulate after pregnancy, obesity and age. The belly button is repositioned and also helps you to tighten up your abdominal muscles in order to create a toned, smoother and stiff stomach profile. Therefore many women will certainly select tummy tuck after pregnancy to revive the fragile muscles as well as improves the appearance of the stomach cavity.

Generally the tummy tuck is coupled with other surgical procedures such as liposuction treatment, breast raising and also breast enlargements. This is referred to as “mommy makeover”, a great decision for ladies who are having kids as well as want to get back their pre-pregnancy physique. The whole tummy tuck process takes 1-5 hours as well as the mini process requires 1-2 hrs. Based on the case, you will need to stay over night in the hospital. After surgical procedure it is important to follow your surgeon s instruction on exercise, diet plan as well as day-to-day activity.

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  • 19 Sep, 2021
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Joey Logano wins his first NASCAR Sprint Cup race of 2016

Tuesday, June 14, 2016

On Sunday, Team Penske driver Joey Logano claimed his first NASCAR Sprint Cup Series win of the 2016 season in the FireKeepers Casino 400 at the Michigan International Speedway in Brooklyn, Michigan. The 200-lap race began with Logano starting from the pole position, and featured nine cautions and fourteen lead changes between eight different drivers.

Despite starting first, Logano was quickly overtaken on the first lap by Furniture Row Racing driver Martin Truex Jr. Truex led the race until Logano reclaimed the first position on lap ten, a position he would keep until the the first cycle of green flag pit stops around lap 40. Logano’s teammate Brad Keselowski took the lead during the pit stop cycle by staying out on the track. Keselowski, low on gasoline, led until a caution came out for a spin by Truex around lap 46. During the caution, Keselowski pitted and returned the lead back to his teammate, who led the race until lap 93.

Two other cautions slowed the race between the first caution and lap 93. The first occurred when Kyle Busch’s engine failed around lap 53, forcing the driver to a last-place finish in the race. The other caution was caused by contact between the cars of Chris Buescher, Dale Earnhardt Jr., and A. J. Allmendinger ten laps later. Between laps 93 and 103, Kyle Larson, Ryan Newman, Keselowski, Jimmie Johnson, and Paul Menard led at least one lap. Logano returned to the lead on lap 104, a few laps before a caution when Jeffrey Earnhardt’s car caught fire. After the caution, Logano remained in first until Hendrick Motorsports driver Chase Elliott passed him on lap 117.

Elliott kept the lead until lap 149, when he was briefly passed by Logano. Elliott retook the lead for three more laps on lap 150 before returning the lead back to Logano, who led until the seventh caution was called around lap 156 for of a collision between Danica Patrick, Brian Scott, and Casey Mears. Logano held the lead on the ensuing restart and led through two more caution periods that were called in the final 50 laps. The first began around lap 164 because of a collision involving Johnson, Trevor Bayne, and Ryan Blaney, while the final caution of the race was called with about ten laps remaining after Denny Hamlin suffered a tire puncture on the front straightaway and collided into the SAFER barrier. On the final restart, Logano retained the first position and led the remainder of the race to capture the fifteenth win of his career.

After the race, Logano, who led a race-high of 138 laps, praised his team, saying “Team Penske gave me a great race car. Everyone did a great job figuring out exactly what this car was going to do. This is Ford’s backyard, Roger [Penske]’s backyard; this is a great win”. Elliott, who finished second in the race, expressed disappointment with his result, claiming he “messed up” by not using the correct gear. Larson, Keselowski, and Kevin Harvick completed the top-five finishers, while Carl Edwards finished in the sixth position. Tony Stewart finished seventh ahead of Austin Dillon and Jamie McMurray, who finished eighth and ninth. Kurt Busch completed the first ten positions with a tenth-place finish. In post-race inspection, Larson’s car did not pass laser inspection, prompting NASCAR to impound his car so it can be further evaluated. Any possible penalties are to be announced in the next week.

In the drivers’ championship, Harvick led Kurt Busch and Keselowski with 526 points. Edwards and Logano were fourth and fifth with 472 and 455 points. Elliott was sixth with 453, followed by Johnson with 441. Truex was scored eighth ahead of Kyle Busch and Matt Kenseth, who completed the top-ten. The 2016 season is scheduled to continue on June 26 with the Toyota/Save Mart 350 at Sonoma Raceway.

Unofficial 2016 FireKeepers Casino 400 Top-10 Race Results
Pos Grid No. Driver Team Manufacturer Laps Led Pts.
1 1 22 Joey Logano Team Penske Ford 200 138 45
2 10 24 Chase Elliott (R) Hendrick Motorsports Chevrolet 200 35 40
3 7 42 Kyle Larson Chip Ganassi Racing Chevrolet 200 1 39
4 15 2 Brad Keselowski Team Penske Ford 200 10 38
5 29 4 Kevin Harvick Stewart-Haas Racing Chevrolet 200 0 36
6 11 19 Carl Edwards Joe Gibbs Racing Toyota 200 0 35
7 3 14 Tony Stewart Stewart-Haas Racing Chevrolet 200 0 34
8 8 3 Austin Dillon Richard Childress Racing Chevrolet 200 0 33
9 14 1 Jamie McMurray Chip Ganassi Racing Chevrolet 200 0 32
10 17 41 Kurt Busch Stewart-Haas Racing Chevrolet 200 0 31
(R) – Rookie
Retrieved from “https://en.wikinews.org/w/index.php?title=Joey_Logano_wins_his_first_NASCAR_Sprint_Cup_race_of_2016&oldid=4264895”
  • 16 Sep, 2021
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Wikinews interviews Victor Kline, leader of newly registered The New Liberals party in Australia

Wednesday, June 16, 2021

On June 3, the New Liberals were officially registered as a political party by the Australian Electoral Commission, enabling them to run candidates for federal elections in the country.

While the party has been in existence for over a year, with member Karen Porter having run in the 2020 Eden-Monaro by-election as an independent candidate, the party applied for registration on December 16.

The party has already faced legal barriers for registration. It shares the “liberal” moniker with Australia’s governing Liberal Party, who called the New Liberals a “cynical attempt to piggyback” on their own name, even presenting a survey from Crosby Textor of over 2000 voters that claimed over two-thirds of voters could percieve a connection between the parties, in an attempt to prevent the party’s registration. Ultimately, the Australian Electoral Commission decided that, on balance, the name of the New Liberals was “sufficiently visually and aurally distinct” from the Liberal Party’s name, and registered the party.

Wikinews spoke with the New Liberals’ party leader Victor Kline via email about the plans of the New Liberals and their policies and values.

Retrieved from “https://en.wikinews.org/w/index.php?title=Wikinews_interviews_Victor_Kline,_leader_of_newly_registered_The_New_Liberals_party_in_Australia&oldid=4626233”
  • 16 Sep, 2021
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Looking For Outdoor Living Options? Consider Fire Pits In Salt Lake City, Ut

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One of the current design trends is expanding a home’s living area by making better use of outdoor spaces. Decks and patios are becoming increasingly important as property owners look for ways to enjoy the outdoors and entertain guests. One of the components now routinely seen in outdoor living spaces is Fire Pits in Salt Lake City UT.

Choosing the Best Options

Fire pits come in a variety of sizes and styles designed to fit virtually any exterior living space. Of course, there are also many materials used to create fire pits, suggesting it should never be difficult to locate a fire pit or fire table to meet a home’s unique needs. The fuel source selected will also be important, as fire pits and tables using wood, natural gas, or LP gas are all readily available. Design experts will generally work closely with property owners to ensure the best fuel option is selected.

Eat, Entertain, and Stay Warm

Fire Pits in Salt Lake City UT can be used as gathering spots for family and friends during most of the year. Even cooler nights will be comfortable when everyone is sitting around a fire pit enjoying each other’s company. Many designs include sitting areas that double as dining spaces. That means everyone can be together as they eat a wonderful dinner. Contractors and design professionals help clients define their needs and select the best fire pits to meet those needs.

Enjoy Flexibility

It’s rather easy to locate a fire pit just about wherever a homeowner feels appropriate. While routing natural gas lines poses some degree of difficulty during installations, opting for wood or LP fire pits makes it possible to install a fire pit just about anywhere. That level of flexibility is ideal for property owners who want to periodically change their deck or patio configuration.

If you’re currently considering a fire pit or table, now is the perfect time to contact a professional for advice. The experts are always available to help homeowners decide which fire pit or fire table would best fulfill their design objectives. If you’ve got questions or would like to explore your outdoor living options, contact Stone Mountain Castings & Design today. Like us on Facebook.

  • 15 Sep, 2021
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International team of scientists studies malaria drug resistance in Southeast Asia

Saturday, August 2, 2014

Researchers from Asia, Africa, Europe, and the United States have mapped resistance of malaria-causing parasite Plasmodium falciparum to antimalarial drug artemisinin, mainly in Southeast Asia; correlated the resistance-causing mutation with slow parasite clearance; and found that prolonged therapy is highly effective against drug-resistant malaria. Their study was published in New England Journal of Medicine on Thursday.

The mutation considered in this study was identified last year as the molecular marker of artemisinin-resistant malaria. The current study found the mutation, located in the propeller domain of a Kelch protein on human chromosome 13, predicted when parasite clearance half-life would exceed five hours with 91.8% sensitivity and 88.4% specificity — usually correct in predicting both when long half-life would occur, and when it wouldn’t. OpenClinica web-based database was used for collection of data which was used to assess parasite clearance rate.

The study found a six-day treatment course effective against artemisinin-resistant malaria. The standard regimen consists of three-day dihydroartemisinin–piperaquine treatment, and had a 25% rate of failure at day 42 in another recent study in Pailin, Cambodia. The prolonged regimen which includes three days of artesunate followed by three days of dihydroartemisinin–piperaquine, has shown 2% rate of failure at day 42 in the same area. Geometric mean of the half-life values were similar in two treatment groups of 60 patients each at each study site: one group received artesunate at a daily dose of 2 mg per patient’s body-weight kilogram and the other 4 mg per kilogram. Afterwards, patients at several study sites were followed for 42 days — Pailin, Cambodia; Attapeu, Laos; Binh Phuoc, Vietnam; Shwe Kyin, Myanmar; and Pingilikani, Kenya — and for 28 days in Kinshasa, DR Congo. The treatment regimens were highly effective at all the study sites.

Support for the study came from the UK Department for International Development, the Worldwide Antimalarial Resistance Network, the Intramural Research Program of the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, and the Bill and Melinda Gates Foundation. Also, the UK-based Wellcome Trust funds one of the participating research organizations, the Mahidol–Oxford Tropical Medicine Research Programme.

Retrieved from “https://en.wikinews.org/w/index.php?title=International_team_of_scientists_studies_malaria_drug_resistance_in_Southeast_Asia&oldid=4285265”
  • 14 Sep, 2021
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