Shrink-wrapped sheep survive: Researchers say ‘Biobag’ artificial uterus, successful on lambs, may one day be suitable for use on premature human babies

Friday, April 28, 2017

In findings published Tuesday in Nature Communications, a team mostly from the Children’s Hospital of Philadelphia announced they have successfully created an artificial womb in which premature lambs can be brought to term. The researchers say this technology could develop into a means of helping premature human babies survive, but it has also drawn concern from bioethicists.

According to first author Emily Partridge and her team, previous efforts at creating an artificial womb have failed because the pumps used, to provide oxygen and nutrients to the developing animal, put too much stress on the heart, causing circulatory failure; and because they used open-fluid systems, which were easily exposed to germs. Partridge et al.’s system uses a closed-fluid apparatus, which they’ve called the Biobag. The sound of a maternal heartbeat was played in the room where the fetuses were kept.

The animals housed in the artificial womb showed normal blood gases and their lungs, brains and nervous systems showed normal development. They opened their eyes and grew wool. When they were removed from the circuit and dissected, their brains, lungs and other organs were found similar to those of lambs delivered by hysterotomy (Cesarean section) when nearly full term.

Although lambs often serve as an experimental model of fetal development, the researchers concede that not all of their findings can be translated to humans. While the lambs’ brains appeared healthy, they also develop certain traits much earlier than human brains, so not all of these effects may be attributable to the Biobag system.

The researchers also acknowledge the startling appearance of a fetus wrapped in plastic. “It is important to consider that the comparator is the extreme premature infant on a ventilator and in an incubator,” reads the official paper. “We feel that parents will be relatively reassured that their fetus is being maintained in a relatively protective and physiologic environment.”

One of the researchers, Dr. Alan Flake, also of the Children’s Hospital of Philadelphia, says the apparatus may be ready for testing on human babies in three to five years. The researchers noted premature birth is the leading cause of infant mortality in the United States, with about nine out of ten infants born at 23 weeks gestation or earlier suffering complications such as mental retardation, deafness, blindness, paralysis, and cerebral palsy. When a fetus is removed from the amniotic fluid and placed on a respirator, the shift from liquid to gas can cause the lungs to stop developing. The most common direct cause of death among premature infants is failure of the lungs to properly oxygenate the blood.

Bioethicist Dena Davis of Lehigh University notes this invention raises several ethical issues. “If it’s a difference between a baby dying rather peacefully and a baby dying under conditions of great stress and discomfort then, no, I don’t think it’s better,” she told National Public Radio. She also notes the problem of babies who would otherwise have died surviving with severe side effects and the implications that this has for the abortion debate: “Up to now, we’ve been either born or not born. This would be halfway born, or something like that.” Scott Gelfand of Oklahoma State University worries that women who would otherwise seek abortion could be pressured into putting their fetuses in Biobags instead or that employers would punish mothers who took maternity leave instead of using an artificial uterus.

“I want to make this very clear: We have no intention and we’ve never had any intention with this technology of extending the limits of viability further back,” Dr. Flake said in response to these issues. “I think when you do that you open a whole new can of worms.” He went on to call gestating fetuses younger than 23 weeks “a pipe dream at this point.”

Friday, January 14, 2005

New York —Media giant Viacom has delayed the launch of its LGBT-themed LOGO channel by more than four months, according to reports. Originally scheduled to launch Feb. 17, the new channel’s debut was delayed until a planned June 30 sign on.

Part of Viacom’s MTV Networks, LOGO has secured carriage on Time Warner cable in Manhattan, RCN and Atlantic Broadband. It is in final negotiations with Comcast, the nation’s largest cable company, which serves the San Francisco Bay Area.

The channel’s management said it will take the extra time to beef up its programming slate and sign on more carriers. LOGO already has secured the rights to such programming as Golden Globe and Emmy-winning Angels in America and films such as Far From Heaven, Philadelphia and The Birdcage.

Original programming includes plans for a string of reality-based series and documentaries with titles such as The Relationship Show, My Fabulous Gay Wedding, and Cruise, which take place about a gay-themed ocean cruise ship.

• “MTV postpones launch of gay channel” — Digital Spy, January 14, 2005
• Cynthia Littleton. “MTV’s Gay Channel Held Back to Summer” — Reuters, January 14, 2005
• Bill Carter. “MTV Postpones the Debut of a Gay Channel” — Reuters, January 14, 2005
• Alonso Duralde. “Logo’s good to go” — The Advocate, January 13, 2005

Thursday, October 3, 2013

A review this week by Wikinews of US Consumer Financial Protection Bureau (CFPB) complaints about mortgages in the United States shows Bank of America leads all lending institutions in complaints.

Since mortgages complaints were recorded in December 2011, 77,622 total have been added to CFPB’s database. 29.2% of these complaints involved Bank of America, with the second most received by Wells Fargo, accounting for 15.5% of all complaints. JPMorgan Chase ranked third by volume of complaints with 9.8%. Ocwen was fourth with 8.7% and Citibank was fifth with 4.8%. Nationstar Mortgage; Green Tree Servicing, LLC; HSBC; PNC Bank; U.S. Bancorp; OneWest Bank; SunTrust Bank; Flagstar Bank; and Select Portfolio Servicing, Inc. each had between 1.0 and 3.8% of total complaints. The remaining 14.4% of all complaints about consumer mortgages were divided between about 530 other lending institutions.

The Motley Fool reported last month that for the past fiscal quarter, the biggest US based mortgage lenders were from first to fifth Wells Fargo, JPMorgan Chase, Bank of America, Quicken Loans and U.S. Bancorp.

According to the US Federal Reserve, debt for family residences stands at US$10.706 trillion for the second quarter of 2013. As of the end of June of this year, Bank of America is the United States’s second largest commercial bank with US$1.343 trillion in domestic assets. Wells Fargo is the fourth largest commercial bank with US$1.251 trillion in domestic assets. JPMorgan Chase is the largest US commercial bank with US$1.329 trillion in domestic assets and US$1.947 trillion in total assets.

The mortgage complaints in the CFPB report include several subproducts. Conventional fixed mortgages account for 27.1% of all complaints. Conventional adjustable mortgages account for 10.0%. FHA mortgages account for 7.7% of all complaints. Home equity loans or lines of credit account for 3.8% of all complaints. VA mortgages are 1.4% of all complaints. Second mortgages and reverse mortgages each account for 0.6% of complaints. The remaining 48.7% of complaints are about other mortgages or other mortgage issues. A few years ago, FHA loans accounted for about 10% of all US mortgages while VA loans accounted for about 3%. Prime loans accounted for over 75% of the market and the rest were subprime mortgages.

California leads all states by volume of complaints with 14768. It is followed by Florida, New York, Georgia and Texas. When complaints are divided by a state’s total population, New Hampshire leads. The state is followed by Washington D.C., Maryland, Georgia and Florida. Complaints do not correlate with national rankings for August’s foreclosure rate by state where Nevada topped the list, followed by Florida, Ohio, Maryland and Delaware.

Two zip codes account for over 1,000 total complaints between them. 565 complaints originated in the 48382 zip code, which is in Commerce Township, Michigan, located in suburban Detroit. 553 complaints originated in the 33071 zip code, in Coral Springs, Florida. According to real estate website Zillow, there are currently 1,033 properties in foreclosure in Coral Springs while Commerce Township only has 131 properties currently in foreclosure. Four other zip codes have 100 plus complaints originating from them. 91730, in Rancho Cucamonga, California, had 158 complaints. 33409, in West Palm Beach, Florida, had 132. 92626, in Costa Mesa, California, had 125 complaints. 92660, in Newport Beach, California, had 122 complaints. Respectively, the towns had 534, 1,068, 153, and 134 properties currently in foreclosure. These numbers are higher than for the cities of a few sampled zip codes where there was only one complaint, such as Gold Hill, Oregon which has 4 properties in foreclosure, and Decatur, Illinois which has 6 properties in foreclosure.

The CFPB categorizes complaints into six categories: “Loan modification, collection,foreclosure” or problems when a person is unable to pay; “Loan servicing, payments, escrow account” or problems with making a payment; “Application, originator, mortgage broker”; “Credit decision / Underwriting”; “Settlement process and costs”, and “Other”. The CFPB says the complaint types indicate consumers “appear to be driven by a desire to seek agreement with their companies on foreclosure alternatives. The complaints indicate that consumer confusion persists around the process and requirements for obtaining loan modifications and refinancing, especially regarding document submission timeframes, payment trial periods, allocation of payments, treatment of income in eligibility calculations, and credit bureau reporting during the evaluation period.” Currently, 59.6% of all complaints against lenders deal with being unable to pay. 25.1% deal with problems in making a payment. 7.0% have to do with the application process.

Of the complaint-heavy zip codes, for 48382 in Commerce Township, Michigan, 98.9% of all complaints have to deal with being unable to pay. Accounting for 23.4% of all mortgage complaints in Commerce Township, 132 of the complaints for being unable to pay were made regarding Bank of America, accounting for 97.8% or all but 3 complaints against them from the zip. 121 of the Bank of America responses in Commerce Township were closed with explanation and 12 were closed with non-monetary relief. 33071 in Coral Springs is different, with 537 of the 553 complaints being categorized under other. Only 11 complaints relate to foreclosure and issues with being able to pay. 92626 in Costa Mesa, where 32% of the mortgage complaints were about Bank of America and 26.4% were about Wells Fargo, had 93.6% of its complaints dealing with being unable to pay. 5 total complaints dealt with payment issues and 3 dealt with applications.

Beyond regional variance in complaint types lodged, the top five mortgage lenders by volume of complaints all had being unable to pay as their top complaint category, ranging between 55.8% for Citibank and 69.4% for Bank of America. Problems with payment accounted for the second largest area of complaints, with Ocwen having the largest percentage of complaints at 31.9% and Bank of America having the smallest at 18.8%. Foreclosure was the top area of complaints for a number of other lending institutions including 1st Alliance Lending, OneWest Bank, Ally Bank, Banco Popular de Puerto Rico, Bank of the West, BMO Harris, BOK Financial Corp, Caliber Home Loans, Inc, Capital One, Deutsche Bank and EverBank.

Nationally, complaints reached a high of 5,840 for January 2013, 1,107 more than the next highest month of April 2013. The total emerging for September is the second lowest since records were first kept in December 2011. On a state by state level, this pattern largely repeats with a major exception for Florida which saw a peak of 849 complaints in June 2012. Then, as now, Florida was one of the top five states in the nation in its foreclosure rate. The national January spike came as the Qualified Mortgage standard required by the The Dodd-Frank Wall Street Reform and Consumer Protection Act of 2010 came into play. It required mortgage lenders to take steps to insure borrowers could repay their mortgages.

Bank of America’s complaint volume follows the national trend, with a spike in January 2013 with 1,925 total complaints. Unlike nationally, the next month by volume of complaints was February of this year with 1,598 complaints. Prior to that, the highest month was May 2012 with 1,418 complaints. The lowest volume of complaints is September this year with 334.

Wells Fargo matched national trends for volume of complaints by month, with the exception of the current month being the lowest on record for number of complaints with 197 compared to the next lowest month, December 2011, when they had 221. JPMorgan’s complaint volume by month spiked in January and March of this year with 504 complaints. April of this year was the next highest month with 493 complaints, edging out May of last year with 488 complaints. September this year is on track to be the lowest month by complaint volume.

The federal government shutdown is unlikely to impact the current mortgage situation in the United States directly for most consumers, though mortgage processing by the Federal Housing Administration could be slower, resulting in fewer mortgages processed.

See the discussion page for instructions on adding schools to this list and for an alphabetically arranged listing of schools.

Due to the damage by Hurricane Katrina and subsequent flooding, a number of colleges and universities in the New Orleans metropolitan area will not be able to hold classes for the fall 2005 semester. It is estimated that 75,000 to 100,000 students have been displaced. [1]. In response, institutions across the United States and Canada are offering late registration for displaced students so that their academic progress is not unduly delayed. Some are offering free or reduced admission to displaced students. At some universities, especially state universities, this offer is limited to residents of the area.

Wednesday, August 16, 2006

Google on Wednesday inaugurated a free city-wide Wi-Fi system in its home town of Mountain View, California. Google insisted that it had no plans to offer a similar service nationwide. Most residents of Mountain View, can connect to the Internet via a Mesh Wi-Fi network for free. Google said that its network “eventually will cover the entire city” and serve as “testing ground for future innovations.” The network is currently setup in downtown Mountain View, and much of the suburbs are yet to be hooked up.

The wireless network (Wi-Fi) covers 90% of Mountain View. It offers maximum data transfer rate of up to 1 Megabit per second, which is slightly slower than DSL.

The system costs about US$1 million to build and uses 380 transceivers mounted on street-lights throughout the 31 km² city. Reviews of the network say that it works smoothly in open areas, but that connections can be patchy in enclosed spaces.

Chris Sacca, Google’s head of special initiatives, said that “the main purpose of his company’s backing local wi-fi access is to clear the way for broadband entrepreneurs and overcome legal roadblocks by established telephone and cable TV providers”.

Mountain View, which has about 72,000 residents, is the largest U.S. city with totally free Internet access available throughout the entire community.

Wednesday, June 11, 2008

On June 4, a report published by the United States Centers for Disease Control and Prevention (CDC) showed that in the past 16 years high school students have become less likely to engage in health risk-related behaviors such as having sex and taking drugs. However, the CDC found that Hispanic students were less likely to have reduced risky behavior when compared to Black and White students in several key areas.

The National Youth Risk Behavior Survey (YRBS) is run by the CDC every two years, and is an anonymous, self-administered survey of students in grades 9 to 12. In the 2007 YRBS, over 14,000 students were surveyed from across 44 U.S. states, 5 territories, and several individual school districts. The combined statistics used results from 39 states and 22 large urban school districts.

The survey showed that males were more likely than females to engage in most behaviors involving violence or risk of unintentional injury, including driving while drinking alcohol, carrying a weapon, and being involved in a physical fight, although females were more likely to have contemplated or attempted suicide. Males were also more likely to have smoked tobacco or marijuana, engaged in heavy drinking, or engaged in sexual intercourse, while females were more likely to have fasted for 24 hours or more, vomited or taken laxatives in order to lose weight.

While the proportions of White and Black students who had ever had sexual intercourse, and who had had sex with four or more partners in their lifetimes, all dropped over the period 1991-2007, there was no change in either of these statistics for the Hispanic population. Compared to their counterparts in the 1990s however, Hispanic students in 2007 were found to be more likely to have used a condom during their most recent sexual intercourse, and less likely to have consumed drugs such as cigarettes, alcohol and marijuana.

Hispanic students were more likely than White or Black students to go without food for 24 hours to lose weight, to take drugs such as heroin or cocaine, to drink alcohol on school property, and to have avoided school on occasion because of safety concerns.

In comparison with previous YRBS results, the survey found that the percentage of students who had ever had sexual intercourse decreased from 54.1% in 1991 to 47.8% in 2007, with a comparable decrease in the percentage who had had four or more sexual partners, from 18.7% to 14.9%. Decreases were also found in the percentage of students who had attempted suicide, who rode in a car with a driver who had been drinking alcohol, and who had smoked marijuana in the past month, but an increase in the percentage who had avoided school on occasion because of safety concerns (from 4.4% in 1993 to 5.5% in 2007).

“We are pleased that more high school students today are doing things that will help them stay healthy and avoiding things that put their health in danger. Unfortunately we are not seeing that same progress among Hispanic teens for certain risk factors,” said Howell Wechsler, Ed.D., MPH, director of CDC’s Division of Adolescent and School Health.

Monday, October 12, 2015

Wikinews interviewed Australian painter Pricasso on his unique artwork created using his penis, and how his art relates to freedom of expression and issues of censorship. He is to be featured at the upcoming adult entertainment event Sexpo Australia in Melbourne this November 5 to November 8.